TLR7 Activation in M-CSF-Dependent Monocyte-Derived Human Macrophages Potentiates Inflammatory Responses and Prompts Neutrophil Recruitment

Toll-like receptor 7 (TLR7) is an endosomal pathogen-associated molecular pattern (PAMP) receptor that senses single-stranded RNA (ssRNA) and whose engagement results in the production of type I IFN and pro-inflammatory cytokines upon viral exposure. Recent genetic studies have established that a dy...

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Detalles Bibliográficos
Autores principales: Simón-Fuentes, Miriam, Herrero, Cristina, Acero-Riaguas, Lucía, Nieto, Concha, Lasala, Fátima, Labiod, Nuria, Luczkowiak, Joanna, Alonso, Bárbara, Delgado, Rafael, Colmenares, María, Corbí, Ángel L., Domínguez-Soto, Ángeles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10315069/
https://www.ncbi.nlm.nih.gov/pubmed/37040733
http://dx.doi.org/10.1159/000530249

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10315069/
https://www.ncbi.nlm.nih.gov/pubmed/37040733
http://dx.doi.org/10.1159/000530249

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