Cargando…

Heroin-Induced Transverse Myelitis in a Chronic Heroin User: A Case Report

Transverse myelitis is a rare but documented sequela of heroin use. While the underlying etiology is not clearly elucidated, the prevailing pathophysiologic mechanism amongst existing literature suggests an immune-mediated hypersensitivity reaction due to heroin insufflation following a long period...

Descripción completa

Detalles Bibliográficos
Autores principales: Hussain, Mueez, Shafer, Drake, Taylor, Joseph, Sivanandham, Ranjit, Vasquez, Hellen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10315196/
https://www.ncbi.nlm.nih.gov/pubmed/37405127
http://dx.doi.org/10.7759/cureus.41286
_version_ 1785067463703003136
author Hussain, Mueez
Shafer, Drake
Taylor, Joseph
Sivanandham, Ranjit
Vasquez, Hellen
author_facet Hussain, Mueez
Shafer, Drake
Taylor, Joseph
Sivanandham, Ranjit
Vasquez, Hellen
author_sort Hussain, Mueez
collection PubMed
description Transverse myelitis is a rare but documented sequela of heroin use. While the underlying etiology is not clearly elucidated, the prevailing pathophysiologic mechanism amongst existing literature suggests an immune-mediated hypersensitivity reaction due to heroin insufflation following a long period of abstinence. Outcomes vary among the limited reports, but prognosis tends to be poor due to an acute and rapidly progressive disease course. Here, we describe a case of extensive transverse myelitis in a chronic heroin user following heroin insufflation. This report hopes to provide greater insight into the underlying cause of this rare phenomenon due to our patient’s discrepancy from the documented norm of heroin abstinence preceding disease onset.
format Online
Article
Text
id pubmed-10315196
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-103151962023-07-03 Heroin-Induced Transverse Myelitis in a Chronic Heroin User: A Case Report Hussain, Mueez Shafer, Drake Taylor, Joseph Sivanandham, Ranjit Vasquez, Hellen Cureus Neurology Transverse myelitis is a rare but documented sequela of heroin use. While the underlying etiology is not clearly elucidated, the prevailing pathophysiologic mechanism amongst existing literature suggests an immune-mediated hypersensitivity reaction due to heroin insufflation following a long period of abstinence. Outcomes vary among the limited reports, but prognosis tends to be poor due to an acute and rapidly progressive disease course. Here, we describe a case of extensive transverse myelitis in a chronic heroin user following heroin insufflation. This report hopes to provide greater insight into the underlying cause of this rare phenomenon due to our patient’s discrepancy from the documented norm of heroin abstinence preceding disease onset. Cureus 2023-07-02 /pmc/articles/PMC10315196/ /pubmed/37405127 http://dx.doi.org/10.7759/cureus.41286 Text en Copyright © 2023, Hussain et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Neurology
Hussain, Mueez
Shafer, Drake
Taylor, Joseph
Sivanandham, Ranjit
Vasquez, Hellen
Heroin-Induced Transverse Myelitis in a Chronic Heroin User: A Case Report
title Heroin-Induced Transverse Myelitis in a Chronic Heroin User: A Case Report
title_full Heroin-Induced Transverse Myelitis in a Chronic Heroin User: A Case Report
title_fullStr Heroin-Induced Transverse Myelitis in a Chronic Heroin User: A Case Report
title_full_unstemmed Heroin-Induced Transverse Myelitis in a Chronic Heroin User: A Case Report
title_short Heroin-Induced Transverse Myelitis in a Chronic Heroin User: A Case Report
title_sort heroin-induced transverse myelitis in a chronic heroin user: a case report
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10315196/
https://www.ncbi.nlm.nih.gov/pubmed/37405127
http://dx.doi.org/10.7759/cureus.41286
work_keys_str_mv AT hussainmueez heroininducedtransversemyelitisinachronicheroinuseracasereport
AT shaferdrake heroininducedtransversemyelitisinachronicheroinuseracasereport
AT taylorjoseph heroininducedtransversemyelitisinachronicheroinuseracasereport
AT sivanandhamranjit heroininducedtransversemyelitisinachronicheroinuseracasereport
AT vasquezhellen heroininducedtransversemyelitisinachronicheroinuseracasereport