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Refining the in vitro release test method for a dapivirine-releasing vaginal ring to match in vivo performance
Previously reported in vitro release test methods for drug-releasing vaginal rings containing poorly water-soluble drugs have described use of water-alcohol systems or surfactant solutions in efforts to maintain sink conditions. Here, as part of efforts to more closely match in vitro and in vivo rel...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10315348/ https://www.ncbi.nlm.nih.gov/pubmed/34674162 http://dx.doi.org/10.1007/s13346-021-01081-7 |