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Development of a HPLC fluorometric method for the quantification of enfuvirtide following in vitro releasing studies on thermosensitive in situ forming gel

Due to the presence of peptidase and protease in the gastrointestinal tract, peptides are subjected to digestion and inactivation when administrated orally. To avoid degradation and maintain the desired efficacy of peptide drugs, there is a demand to develop transdermal and intradermal delivery syst...

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Detalles Bibliográficos
Autores principales: Li, Huanhuan, Anjani, Qonita Kurnia, McGuckin, Mary B., Himawan, Achmad, Li, Mingshan, Donnelly, Ryan F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10315353/
https://www.ncbi.nlm.nih.gov/pubmed/37120679
http://dx.doi.org/10.1007/s13346-023-01344-5