Light-responsive biomaterials for ocular drug delivery

Light-responsive biomaterials can be used for the delivery of therapeutic drugs and nucleic acids, where the tunable/precise delivery of payload highlights the potential of such biomaterials for treating a variety of conditions. The translucency of eyes and advances of laser technology in ophthalmol...

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Autores principales: Abdelmohsen, Hend A. M., Copeland, Nikki A., Hardy, John G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10315357/
https://www.ncbi.nlm.nih.gov/pubmed/35751001
http://dx.doi.org/10.1007/s13346-022-01196-5
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author Abdelmohsen, Hend A. M.
Copeland, Nikki A.
Hardy, John G.
author_facet Abdelmohsen, Hend A. M.
Copeland, Nikki A.
Hardy, John G.
author_sort Abdelmohsen, Hend A. M.
collection PubMed
description Light-responsive biomaterials can be used for the delivery of therapeutic drugs and nucleic acids, where the tunable/precise delivery of payload highlights the potential of such biomaterials for treating a variety of conditions. The translucency of eyes and advances of laser technology in ophthalmology make light-responsive delivery of drugs feasible. Importantly, light can be applied in a non-invasive fashion; therefore, light-triggered drug delivery systems have great potential for clinical impact. This review will examine various types of light-responsive polymers and the chemistry that underpins their application as ophthalmic drug delivery systems. GRAPHICAL ABSTRACT: [Image: see text]
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spelling pubmed-103153572023-07-04 Light-responsive biomaterials for ocular drug delivery Abdelmohsen, Hend A. M. Copeland, Nikki A. Hardy, John G. Drug Deliv Transl Res Original Article Light-responsive biomaterials can be used for the delivery of therapeutic drugs and nucleic acids, where the tunable/precise delivery of payload highlights the potential of such biomaterials for treating a variety of conditions. The translucency of eyes and advances of laser technology in ophthalmology make light-responsive delivery of drugs feasible. Importantly, light can be applied in a non-invasive fashion; therefore, light-triggered drug delivery systems have great potential for clinical impact. This review will examine various types of light-responsive polymers and the chemistry that underpins their application as ophthalmic drug delivery systems. GRAPHICAL ABSTRACT: [Image: see text] Springer US 2022-06-24 2023 /pmc/articles/PMC10315357/ /pubmed/35751001 http://dx.doi.org/10.1007/s13346-022-01196-5 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Article
Abdelmohsen, Hend A. M.
Copeland, Nikki A.
Hardy, John G.
Light-responsive biomaterials for ocular drug delivery
title Light-responsive biomaterials for ocular drug delivery
title_full Light-responsive biomaterials for ocular drug delivery
title_fullStr Light-responsive biomaterials for ocular drug delivery
title_full_unstemmed Light-responsive biomaterials for ocular drug delivery
title_short Light-responsive biomaterials for ocular drug delivery
title_sort light-responsive biomaterials for ocular drug delivery
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10315357/
https://www.ncbi.nlm.nih.gov/pubmed/35751001
http://dx.doi.org/10.1007/s13346-022-01196-5
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