SIRT6 is an epigenetic repressor of thoracic aortic aneurysms via inhibiting inflammation and senescence

Thoracic aortic aneurysms (TAAs) develop asymptomatically and are characterized by dilatation of the aorta. This is considered a life-threating vascular disease due to the risk of aortic rupture and without effective treatments. The current understanding of the pathogenesis of TAA is still limited,...

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Detalles Bibliográficos
Autores principales: Ding, Yang-Nan, Wang, Ting-Ting, Lv, Shuang-Jie, Tang, Xiaoqiang, Wei, Zi-Yu, Yao, Fang, Xu, Han-Shi, Chen, Yi-Nan, Wang, Xiao-Man, Wang, Hui-Yu, Wang, He-Ping, Zhang, Zhu-Qin, Zhao, Xiang, Hao, De-Long, Sun, Li-Hong, Zhou, Zhou, Wang, Li, Chen, Hou-Zao, Liu, De-Pei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10315397/
https://www.ncbi.nlm.nih.gov/pubmed/37394473
http://dx.doi.org/10.1038/s41392-023-01456-x

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