Th1 Cells Alter the Inflammatory Signature of IL-6 by Channeling STAT Transcription Factors to Alu-like Retroelements

Cytokines that signal via STAT1 and STAT3 transcription factors instruct decisions affecting tissue homeostasis, antimicrobial host defense, and inflammation-induced tissue injury. To understand the coordination of these activities, we applied RNA sequencing, chromatin immunoprecipitation sequencing...

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Detalles Bibliográficos
Autores principales: Millrine, David, Cardus Figueras, Ana, Uceda Fernandez, Javier, Andrews, Robert, Szomolay, Barbara, Cossins, Benjamin C., Rice, Christopher M., Li, Jasmine, Tyrrell, Victoria J., McLeod, Louise, Holmans, Peter, O’Donnell, Valerie B., Taylor, Philip R., Turner, Stephen J., Jenkins, Brendan J., Jones, Gareth W., Topley, Nicholas, Williams, Nigel M., Jones, Simon A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAI 2023
Materias:
Innate Immunity and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10315439/
https://www.ncbi.nlm.nih.gov/pubmed/37272871
http://dx.doi.org/10.4049/jimmunol.2300114

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