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A case report: The first show phenomenon in the treatment of spinal cord injury with Regentime procedure using autologous bone marrow‐derived stem cells
KEY CLINICAL MESSAGE: Promising outcomes are shown in this case report using the Regentime procedure and autologous stem cells to treat spinal cord injury. The observed “First Show Phenomenon” provides valuable insights into the therapy's potential for spinal cord injury. ABSTRACT: This case re...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10315442/ https://www.ncbi.nlm.nih.gov/pubmed/37405041 http://dx.doi.org/10.1002/ccr3.7568 |
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author | Boulos, Rita T. Nemer, Lea I. Mansour, Vanessa J. Najjoum, Cynthia F. Asmar, Elsa A. Abi Chahine, Nassim H. |
author_facet | Boulos, Rita T. Nemer, Lea I. Mansour, Vanessa J. Najjoum, Cynthia F. Asmar, Elsa A. Abi Chahine, Nassim H. |
author_sort | Boulos, Rita T. |
collection | PubMed |
description | KEY CLINICAL MESSAGE: Promising outcomes are shown in this case report using the Regentime procedure and autologous stem cells to treat spinal cord injury. The observed “First Show Phenomenon” provides valuable insights into the therapy's potential for spinal cord injury. ABSTRACT: This case report demonstrates “the first show phenomenon” following Regentime stem cell therapy applied to a spinal cord injury patient. A 40‐year‐old gentleman sustained a ballistic injury at the level of T9, resulting in complete bilateral motor and sensory loss from T9 and below. He was treated with autologous bone marrow‐derived mononuclear stem cells injected into his spinal canal 2.5 years after his injury. Follow‐up during the first‐week posttransplantation showed early symptom improvement termed “the first show phenomenon.” He regained sensation to light touch in his lower limbs by the end of week 1 and reported no serious implications or complications. |
format | Online Article Text |
id | pubmed-10315442 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-103154422023-07-04 A case report: The first show phenomenon in the treatment of spinal cord injury with Regentime procedure using autologous bone marrow‐derived stem cells Boulos, Rita T. Nemer, Lea I. Mansour, Vanessa J. Najjoum, Cynthia F. Asmar, Elsa A. Abi Chahine, Nassim H. Clin Case Rep Case Report KEY CLINICAL MESSAGE: Promising outcomes are shown in this case report using the Regentime procedure and autologous stem cells to treat spinal cord injury. The observed “First Show Phenomenon” provides valuable insights into the therapy's potential for spinal cord injury. ABSTRACT: This case report demonstrates “the first show phenomenon” following Regentime stem cell therapy applied to a spinal cord injury patient. A 40‐year‐old gentleman sustained a ballistic injury at the level of T9, resulting in complete bilateral motor and sensory loss from T9 and below. He was treated with autologous bone marrow‐derived mononuclear stem cells injected into his spinal canal 2.5 years after his injury. Follow‐up during the first‐week posttransplantation showed early symptom improvement termed “the first show phenomenon.” He regained sensation to light touch in his lower limbs by the end of week 1 and reported no serious implications or complications. John Wiley and Sons Inc. 2023-07-02 /pmc/articles/PMC10315442/ /pubmed/37405041 http://dx.doi.org/10.1002/ccr3.7568 Text en © 2023 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Boulos, Rita T. Nemer, Lea I. Mansour, Vanessa J. Najjoum, Cynthia F. Asmar, Elsa A. Abi Chahine, Nassim H. A case report: The first show phenomenon in the treatment of spinal cord injury with Regentime procedure using autologous bone marrow‐derived stem cells |
title | A case report: The first show phenomenon in the treatment of spinal cord injury with Regentime procedure using autologous bone marrow‐derived stem cells |
title_full | A case report: The first show phenomenon in the treatment of spinal cord injury with Regentime procedure using autologous bone marrow‐derived stem cells |
title_fullStr | A case report: The first show phenomenon in the treatment of spinal cord injury with Regentime procedure using autologous bone marrow‐derived stem cells |
title_full_unstemmed | A case report: The first show phenomenon in the treatment of spinal cord injury with Regentime procedure using autologous bone marrow‐derived stem cells |
title_short | A case report: The first show phenomenon in the treatment of spinal cord injury with Regentime procedure using autologous bone marrow‐derived stem cells |
title_sort | case report: the first show phenomenon in the treatment of spinal cord injury with regentime procedure using autologous bone marrow‐derived stem cells |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10315442/ https://www.ncbi.nlm.nih.gov/pubmed/37405041 http://dx.doi.org/10.1002/ccr3.7568 |
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