Cargando…

Low potential of persistence and dissemination of antimicrobial-resistant Enterobacterales by wild nutria (Myocastor coypus) in a local river of Gifu Prefecture

Environmental pollution caused by antimicrobial resistance is a global public health concern. To investigate the contribution of nutrias (Myocastor coypus) to the presence of extended-spectrum β-lactamase (ESBL)–producing Enterobacterales in the Ijira River, prevalence of ESBL–producing Enterobacter...

Descripción completa

Detalles Bibliográficos
Autores principales: NAKATSUBO, Tomoki, NAKAMURA, Kohei, OMATSU, Tsutomu, SUGIYAMA, Michiyo, ASAI, Tetsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10315553/
https://www.ncbi.nlm.nih.gov/pubmed/37150602
http://dx.doi.org/10.1292/jvms.23-0042
_version_ 1785067525927600128
author NAKATSUBO, Tomoki
NAKAMURA, Kohei
OMATSU, Tsutomu
SUGIYAMA, Michiyo
ASAI, Tetsuo
author_facet NAKATSUBO, Tomoki
NAKAMURA, Kohei
OMATSU, Tsutomu
SUGIYAMA, Michiyo
ASAI, Tetsuo
author_sort NAKATSUBO, Tomoki
collection PubMed
description Environmental pollution caused by antimicrobial resistance is a global public health concern. To investigate the contribution of nutrias (Myocastor coypus) to the presence of extended-spectrum β-lactamase (ESBL)–producing Enterobacterales in the Ijira River, prevalence of ESBL–producing Enterobacterales in their feces was examined using deoxycholate-hydrogen sulfide-lactose agar containing cefotaxime. Additionally, the composition of the fecal microbiota of nutria was examined using DNA metabarcoding analysis of the 16S ribosomal RNA gene and compared with that of Amami rabbit, deer, fox, and raccoon dog. The absence of ESBL–producing Enterobacterales and substantially lower abundance of Enterobacterales was observed in the feces of nutrias than in those of other wild mammals. Our results suggest the low potential of antimicrobial-resistant Enterobacterales persistence and dissemination by nutria.
format Online
Article
Text
id pubmed-10315553
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher The Japanese Society of Veterinary Science
record_format MEDLINE/PubMed
spelling pubmed-103155532023-07-04 Low potential of persistence and dissemination of antimicrobial-resistant Enterobacterales by wild nutria (Myocastor coypus) in a local river of Gifu Prefecture NAKATSUBO, Tomoki NAKAMURA, Kohei OMATSU, Tsutomu SUGIYAMA, Michiyo ASAI, Tetsuo J Vet Med Sci Public Health Environmental pollution caused by antimicrobial resistance is a global public health concern. To investigate the contribution of nutrias (Myocastor coypus) to the presence of extended-spectrum β-lactamase (ESBL)–producing Enterobacterales in the Ijira River, prevalence of ESBL–producing Enterobacterales in their feces was examined using deoxycholate-hydrogen sulfide-lactose agar containing cefotaxime. Additionally, the composition of the fecal microbiota of nutria was examined using DNA metabarcoding analysis of the 16S ribosomal RNA gene and compared with that of Amami rabbit, deer, fox, and raccoon dog. The absence of ESBL–producing Enterobacterales and substantially lower abundance of Enterobacterales was observed in the feces of nutrias than in those of other wild mammals. Our results suggest the low potential of antimicrobial-resistant Enterobacterales persistence and dissemination by nutria. The Japanese Society of Veterinary Science 2023-05-02 2023-06 /pmc/articles/PMC10315553/ /pubmed/37150602 http://dx.doi.org/10.1292/jvms.23-0042 Text en ©2023 The Japanese Society of Veterinary Science https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License. (CC-BY-NC-ND 4.0: https://creativecommons.org/licenses/by-nc-nd/4.0/)
spellingShingle Public Health
NAKATSUBO, Tomoki
NAKAMURA, Kohei
OMATSU, Tsutomu
SUGIYAMA, Michiyo
ASAI, Tetsuo
Low potential of persistence and dissemination of antimicrobial-resistant Enterobacterales by wild nutria (Myocastor coypus) in a local river of Gifu Prefecture
title Low potential of persistence and dissemination of antimicrobial-resistant Enterobacterales by wild nutria (Myocastor coypus) in a local river of Gifu Prefecture
title_full Low potential of persistence and dissemination of antimicrobial-resistant Enterobacterales by wild nutria (Myocastor coypus) in a local river of Gifu Prefecture
title_fullStr Low potential of persistence and dissemination of antimicrobial-resistant Enterobacterales by wild nutria (Myocastor coypus) in a local river of Gifu Prefecture
title_full_unstemmed Low potential of persistence and dissemination of antimicrobial-resistant Enterobacterales by wild nutria (Myocastor coypus) in a local river of Gifu Prefecture
title_short Low potential of persistence and dissemination of antimicrobial-resistant Enterobacterales by wild nutria (Myocastor coypus) in a local river of Gifu Prefecture
title_sort low potential of persistence and dissemination of antimicrobial-resistant enterobacterales by wild nutria (myocastor coypus) in a local river of gifu prefecture
topic Public Health
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10315553/
https://www.ncbi.nlm.nih.gov/pubmed/37150602
http://dx.doi.org/10.1292/jvms.23-0042
work_keys_str_mv AT nakatsubotomoki lowpotentialofpersistenceanddisseminationofantimicrobialresistantenterobacteralesbywildnutriamyocastorcoypusinalocalriverofgifuprefecture
AT nakamurakohei lowpotentialofpersistenceanddisseminationofantimicrobialresistantenterobacteralesbywildnutriamyocastorcoypusinalocalriverofgifuprefecture
AT omatsutsutomu lowpotentialofpersistenceanddisseminationofantimicrobialresistantenterobacteralesbywildnutriamyocastorcoypusinalocalriverofgifuprefecture
AT sugiyamamichiyo lowpotentialofpersistenceanddisseminationofantimicrobialresistantenterobacteralesbywildnutriamyocastorcoypusinalocalriverofgifuprefecture
AT asaitetsuo lowpotentialofpersistenceanddisseminationofantimicrobialresistantenterobacteralesbywildnutriamyocastorcoypusinalocalriverofgifuprefecture