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Always stressed but never exhausted: how stem cells in myeloid neoplasms avoid extinction in inflammatory conditions
Chronic or recurrent episodes of acute inflammation cause attrition of normal hematopoietic stem cells (HSCs) that can lead to hematopoietic failure but they drive progression in myeloid malignancies and their precursor clonal hematopoiesis. Mechanistic parallels exist between hematopoiesis in chron...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society of Hematology
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10315634/ https://www.ncbi.nlm.nih.gov/pubmed/36947811 http://dx.doi.org/10.1182/blood.2022017152 |