Transcriptomic evidence for tumor‐specific beneficial or adverse effects of TGFβ pathway inhibition on the prognosis of patients with liver cancer

Therapeutic targeting of the transforming growth factor beta (TGFβ) pathway in cancer represents a clinical challenge since TGFβ exhibits either tumor suppressive or tumor promoting properties, depending on the tumor stage. Thus, treatment with galunisertib, a small molecule inhibitor of TGFβ recept...

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Detalles Bibliográficos
Autores principales: Desoteux, Matthis, Maillot, Betty, Bévant, Kevin, Ferlier, Tanguy, Leroux, Raffaële, Angenard, Gaëlle, Louis, Corentin, Sulpice, Laurent, Boudjema, Karim, Coulouarn, Cédric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10315808/
https://www.ncbi.nlm.nih.gov/pubmed/37195148
http://dx.doi.org/10.1002/2211-5463.13647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10315808/
https://www.ncbi.nlm.nih.gov/pubmed/37195148
http://dx.doi.org/10.1002/2211-5463.13647

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