Cargando…

High growth hormone serum partially protects mice against Trypanosoma cruzi infection

Chagas disease (CD) is one of the most devasting parasitic diseases in the Americas, affecting 7–8 million people worldwide. In vitro and in vivo experiments have demonstrated that growth hormone (GH) serum levels decrease as CD progresses. Interestingly, inactivating mutations in the GH receptor in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mora‐Criollo, Patricia, Basu, Reetobrata, Qian, Yanrong, Funk, Kevin, Bell, Stephen, Young, Jonathan A., List, Edward O., Costales, Jaime A., Guevara‐Aguirre, Jaime, Grijalva, Mario J., Kopchick, John J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10315831/ https://www.ncbi.nlm.nih.gov/pubmed/37163287 http://dx.doi.org/10.1002/2211-5463.13627

Ejemplares similares

The Effect of the GH/IGF-1 Axis During Trypanosoma Cruzi Infection
por: Mora-Criollo, Patricia, et al.
Publicado: (2021)

THU545 Growth Hormone Receptor Antagonist As A Novel Combination Therapy Against Triple Negative Breast Cancer
por: Mora-Criollo, Patricia, et al.
Publicado: (2023)

SAT-181 Characterization of Adult Growth Hormone Receptor Gene-Disrupted Mice
por: Duran-Ortiz, Silvana, et al.
Publicado: (2019)

Sex, Subdivision, and Domestic Dispersal of Trypanosoma cruzi Lineage I in Southern Ecuador
por: Ocaña-Mayorga, Sofía, et al.
Publicado: (2010)

Meiotic sex in Chagas disease parasite Trypanosoma cruzi
por: Schwabl, Philipp, et al.
Publicado: (2019)

Remarkable genetic diversity of Trypanosoma cruzi and Trypanosoma rangeli in two localities of southern Ecuador identified via deep sequencing of mini-exon gene amplicons
por: Maiguashca Sánchez, Jalil, et al.
Publicado: (2020)

Fatal acute Chagas disease by Trypanosoma cruzi DTU TcI, Ecuador
por: Calvopina, Manuel, et al.
Publicado: (2020)

The effects of growth hormone on therapy resistance in cancer
por: Basu, Reetobrata, et al.
Publicado: (2019)

Growth Hormone Receptor Gene Disruption in Mature-Adult Mice Improves Glucose Metabolism and Lifespan in Females
por: Duran-Ortiz, Silvana, et al.
Publicado: (2021)

SAT-LB054 Growth Hormone Receptor (GHR) Antagonism Suppresses Hepatocellular Carcinoma Growth in a Syngeneic Mouse Model
por: Mathes, Samuel, et al.
Publicado: (2019)

Growth Hormone Receptor Inhibition Sensitizes Human Pancreatic Cancer to Chemotherapy Treatments
por: Basu, Reetobrata, et al.
Publicado: (2021)

SUN-336 Autocrine / Paracrine Growth Hormone (GH) Drives Multimodal Therapy Resistance in Growth Hormone Receptor (GHR)-expressing Human Cancers
por: Basu, Reetobrata, et al.
Publicado: (2019)

OR0304 Novel Dual Antagonists Of The Growth Hormone Receptor And The Prolactin Receptor
por: Basu, Reetobrata, et al.
Publicado: (2023)

Effects of Growth Hormone on Pancreatic Cancer Derived Exosomes
por: Kulkarni, Prateek, et al.
Publicado: (2021)

Growth hormone receptor gene disruption in mature‐adult mice improves male insulin sensitivity and extends female lifespan
por: Duran‐Ortiz, Silvana, et al.
Publicado: (2021)

A Novel Peptide Antagonist of the Human Growth Hormone Receptor
por: Basu, Reetobrata None, et al.
Publicado: (2021)

Effects of Growth Hormone in Human Melanoma Drug Resistance
por: Arora, Pranay, et al.
Publicado: (2021)

SAT-LB053 Investigating the Effects of Growth Hormone on Tumor-derived Exosome Output and Content
por: Kulkarni, Prateek, et al.
Publicado: (2019)

Culture-free genome-wide locus sequence typing (GLST) provides new perspectives on Trypanosoma cruzi dispersal and infection complexity
por: Schwabl, Philipp, et al.
Publicado: (2020)

Growth hormone receptor antagonism downregulates ATP-binding cassette transporters contributing to improved drug efficacy against melanoma and hepatocarcinoma in vivo
por: Basu, Reetobrata, et al.
Publicado: (2022)

Targeting growth hormone receptor in human melanoma cells attenuates tumor progression and epithelial mesenchymal transition via suppression of multiple oncogenic pathways
por: Basu, Reetobrata, et al.
Publicado: (2017)

First description of Trypanosoma cruzi human infection in Esmeraldas province, Ecuador
por: Guevara, Ángel, et al.
Publicado: (2014)

THU549 Targeting The Growth Hormone Receptor Attenuates Tumor Exosome Mediated Propagation Of Chemoresistance In Melanoma
por: Kulkarni, Prateek, et al.
Publicado: (2023)

In vitro susceptibility of Trypanosoma cruzi discrete typing units (DTUs) to benznidazole: A systematic review and meta-analysis
por: Vela, Andrea, et al.
Publicado: (2021)

A Soluble Factor from Trypanosoma cruzi Inhibits Transforming Growth Factor-ß-Induced MAP Kinase Activation and Gene Expression in Dermal Fibroblasts
por: Mott, G. Adam, et al.
Publicado: (2011)

Cytokine-dependent and–independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling
por: Costales, Jaime A, et al.
Publicado: (2009)

MON-311 GH Action Upregulates ABC Transporters And EMT Markers In A Syngeneic Melanoma Mouse Model
por: Qian, Yanrong, et al.
Publicado: (2019)

Growth Hormone Upregulates Mediators of Melanoma Drug Efflux and Epithelial-to-Mesenchymal Transition In Vitro and In Vivo
por: Qian, Yanrong, et al.
Publicado: (2020)

Parasite-Mediated Remodeling of the Host Microfilament Cytoskeleton Enables Rapid Egress of Trypanosoma cruzi following Membrane Rupture
por: Ferreira, Eden R., et al.
Publicado: (2021)

Growth Hormone Upregulates Melanocyte-Inducing Transcription Factor Expression and Activity via JAK2-STAT5 and SRC Signaling in GH Receptor-Positive Human Melanoma
por: Basu, Reetobrata, et al.
Publicado: (2019)

MON-480 Reduced Respiration Observed In Isolated Liver Mitochondria Of Long-lived GHR-/- Mice At Early Ages
por: Funk, Kevin, et al.
Publicado: (2019)

Repeat-Driven Generation of Antigenic Diversity in a Major Human Pathogen, Trypanosoma cruzi
por: Talavera-López, Carlos, et al.
Publicado: (2021)

OR05-04 Growth Hormone Receptor Antagonism Markedly Improves Therapeutic Response In Mouse Models Of Melanoma, Liver Cancer, Pancreatic Cancer And Cholangiocarcinoma
por: Basu, Reetobrata, et al.
Publicado: (2023)

Secretome analysis of Trypanosoma cruzi by proteomics studies
por: Brossas, Jean-Yves, et al.
Publicado: (2017)

Triatomine Feeding Profiles and Trypanosoma cruzi Infection, Implications in Domestic and Sylvatic Transmission Cycles in Ecuador
por: Ocaña-Mayorga, Sofía, et al.
Publicado: (2021)

The N-myristoylome of Trypanosoma cruzi
por: Roberts, Adam J., et al.
Publicado: (2016)

Mice with gene alterations in the GH and IGF family
por: Qian, Yanrong, et al.
Publicado: (2021)

Molecular and antigenic characterization of Trypanosoma cruzi TolT proteins
por: Lobo, Maite, et al.
Publicado: (2019)

Bats, Trypanosomes, and Triatomines in Ecuador: New Insights into the Diversity, Transmission, and Origins of Trypanosoma cruzi and Chagas Disease
por: Pinto, C. Miguel, et al.
Publicado: (2015)

Chagas disease reactivation in a heart transplant patient infected by domestic Trypanosoma cruzi discrete typing unit I (TcI(DOM))
por: Costales, Jaime A., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_paustdtm63npck771r1f1hk687