Paxbp1 is indispensable for the survival of CD4 and CD8 double-positive thymocytes

The lifespan of double-positive (DP) thymocytes is critical for intrathymic development and shaping the peripheral T cell repertoire. However, the molecular mechanisms that control DP thymocyte survival remain poorly understood. Paxbp1 is a conserved nuclear protein that has been reported to play im...

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Detalles Bibliográficos
Autores principales: Li, Wenting, Yang, Yang, Liu, Shenglin, Zhang, Dongsheng, Ren, Xuanyao, Tang, Mindan, Zhang, Wei, Chen, Xiaofan, Huang, Cong, Yu, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10315898/
https://www.ncbi.nlm.nih.gov/pubmed/37404821
http://dx.doi.org/10.3389/fimmu.2023.1183367

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10315898/
https://www.ncbi.nlm.nih.gov/pubmed/37404821
http://dx.doi.org/10.3389/fimmu.2023.1183367

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