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Paxbp1 is indispensable for the survival of CD4 and CD8 double-positive thymocytes
The lifespan of double-positive (DP) thymocytes is critical for intrathymic development and shaping the peripheral T cell repertoire. However, the molecular mechanisms that control DP thymocyte survival remain poorly understood. Paxbp1 is a conserved nuclear protein that has been reported to play im...
Autores principales: | Li, Wenting, Yang, Yang, Liu, Shenglin, Zhang, Dongsheng, Ren, Xuanyao, Tang, Mindan, Zhang, Wei, Chen, Xiaofan, Huang, Cong, Yu, Bo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10315898/ https://www.ncbi.nlm.nih.gov/pubmed/37404821 http://dx.doi.org/10.3389/fimmu.2023.1183367 |
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