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Fatal intracranial haemorrhage in acute promyelocytic leukemia patients with short isoform of PML-RARα: Review of molecular and radiological data

Three major PML-RARα fusion gene transcripts (long [bcr1], variant [bcr2], and short [bcr3]) are currently used in clinical laboratories for the diagnosis and treatment monitoring of APL patients. Despite highly improved outcome, relapse and intracranial haemorrhage that may lead to early death is s...

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Detalles Bibliográficos
Autores principales: Abudawood, Manal, Alorini, Hanan, Samman, Manar A., Bashir, Salman M., AlSwayed, Azizah, Binhassan, Sarah, Peer-Zada, Abdul Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10316003/
https://www.ncbi.nlm.nih.gov/pubmed/37405260
http://dx.doi.org/10.1016/j.sjbs.2023.103710