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Regulation of cGAS and STING signaling during inflammation and infection
Stimulator of interferon genes (STING) is a sensor of cyclic dinucleotides including cyclic GMP-AMP, which is produced by cyclic GMP-AMP synthase (cGAS) in response to cytosolic DNA. The cGAS–STING signaling pathway regulates both innate and adaptive immune responses, as well as fundamental cellular...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10316007/ https://www.ncbi.nlm.nih.gov/pubmed/37247757 http://dx.doi.org/10.1016/j.jbc.2023.104866 |