Loss of the mitochondrial protein Abcb10 results in altered arginine metabolism in MEL and K562 cells and nutrient stress signaling through ATF4

Abcb10 is a mitochondrial membrane protein involved in hemoglobinization of red cells. Abcb10 topology and ATPase domain localization suggest it exports a substrate, likely biliverdin, out of mitochondria that is necessary for hemoglobinization. In this study, we generated Abcb10 deletion cell lines...

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Detalles Bibliográficos
Autores principales: Miljkovic, Marisa, Seguin, Alexandra, Jia, Xuan, Cox, James E., Catrow, Jonathan Leon, Bergonia, Hector, Phillips, John D., Stephens, W. Zac, Ward, Diane M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10316008/
https://www.ncbi.nlm.nih.gov/pubmed/37269954
http://dx.doi.org/10.1016/j.jbc.2023.104877

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10316008/
https://www.ncbi.nlm.nih.gov/pubmed/37269954
http://dx.doi.org/10.1016/j.jbc.2023.104877

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