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Loss of the mitochondrial protein Abcb10 results in altered arginine metabolism in MEL and K562 cells and nutrient stress signaling through ATF4
Abcb10 is a mitochondrial membrane protein involved in hemoglobinization of red cells. Abcb10 topology and ATPase domain localization suggest it exports a substrate, likely biliverdin, out of mitochondria that is necessary for hemoglobinization. In this study, we generated Abcb10 deletion cell lines...
Autores principales: | Miljkovic, Marisa, Seguin, Alexandra, Jia, Xuan, Cox, James E., Catrow, Jonathan Leon, Bergonia, Hector, Phillips, John D., Stephens, W. Zac, Ward, Diane M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10316008/ https://www.ncbi.nlm.nih.gov/pubmed/37269954 http://dx.doi.org/10.1016/j.jbc.2023.104877 |
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