Single-cell and spatial transcriptomics reveal 5-methylcytosine RNA methylation regulators immunologically reprograms tumor microenvironment characterizations, immunotherapy response and precision treatment of clear cell renal cell carcinoma

Clear cell Renal Cell Carcinoma (ccRCC) is a highly heterogeneous disease, making it challenging to predict prognosis and therapy efficacy. In this study, we aimed to explore the role of 5-methylcytosine (m5C) RNA modification in ccRCC and its potential as a predictor for therapy response and overal...

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Detalles Bibliográficos
Autores principales: Gui, Cheng-Peng, Wei, Jin-Huan, Zhang, Chi, Tang, Yi-Ming, Shu, Guan-Nan, Wu, Rong-Pei, Luo, Jun-Hang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10316128/
https://www.ncbi.nlm.nih.gov/pubmed/37379773
http://dx.doi.org/10.1016/j.tranon.2023.101726

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