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Unusual extraneural metastasis of glioblastoma
BACKGROUND: Glioblastoma (GB) is the most common and aggressive malignant brain tumor in adults. Extracranial metastases are very rare, been described in the lungs, soft tissue, or the intraspinal space. CASE DESCRIPTION: Through a PubMed-based bibliographic search, the authors reviewed the cases re...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Scientific Scholar
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10316183/ https://www.ncbi.nlm.nih.gov/pubmed/37404487 http://dx.doi.org/10.25259/SNI_191_2023 |
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author | Achi, Jimmy Achi, Xavier Wong Veintimilla, Paula Cueva, Janina |
author_facet | Achi, Jimmy Achi, Xavier Wong Veintimilla, Paula Cueva, Janina |
author_sort | Achi, Jimmy |
collection | PubMed |
description | BACKGROUND: Glioblastoma (GB) is the most common and aggressive malignant brain tumor in adults. Extracranial metastases are very rare, been described in the lungs, soft tissue, or the intraspinal space. CASE DESCRIPTION: Through a PubMed-based bibliographic search, the authors reviewed the cases reported in the literature to date, emphasizing the epidemiology and pathophysiology of this rare condition. A clinical case of a 46-year-old man with an initial diagnosis of gliosarcoma, who received complete surgical and adjuvant treatment and later recurred as GB with incidental finding of a lung tumor, whose pathology reported metastasis of the primary, is illustrated. CONCLUSION: Understanding the pathophysiology, it is likely that the incidence of extraneural metastases may continue to increase. Considering improvements in diagnostic techniques that allow early diagnosis, as well as advances in neurosurgical therapy and multimodal management with the aim of improving patient survival, the period in which malignant cells can spread and form extracranial metastases could increase. When screening should be performed to detect metastases in these patients is still not clear. The neuro-oncologists should pay attention to the systematic survey for extraneural metastasis of the GB. Timely detection and early treatment improve overall quality of patients’ life. |
format | Online Article Text |
id | pubmed-10316183 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Scientific Scholar |
record_format | MEDLINE/PubMed |
spelling | pubmed-103161832023-07-04 Unusual extraneural metastasis of glioblastoma Achi, Jimmy Achi, Xavier Wong Veintimilla, Paula Cueva, Janina Surg Neurol Int Case Report BACKGROUND: Glioblastoma (GB) is the most common and aggressive malignant brain tumor in adults. Extracranial metastases are very rare, been described in the lungs, soft tissue, or the intraspinal space. CASE DESCRIPTION: Through a PubMed-based bibliographic search, the authors reviewed the cases reported in the literature to date, emphasizing the epidemiology and pathophysiology of this rare condition. A clinical case of a 46-year-old man with an initial diagnosis of gliosarcoma, who received complete surgical and adjuvant treatment and later recurred as GB with incidental finding of a lung tumor, whose pathology reported metastasis of the primary, is illustrated. CONCLUSION: Understanding the pathophysiology, it is likely that the incidence of extraneural metastases may continue to increase. Considering improvements in diagnostic techniques that allow early diagnosis, as well as advances in neurosurgical therapy and multimodal management with the aim of improving patient survival, the period in which malignant cells can spread and form extracranial metastases could increase. When screening should be performed to detect metastases in these patients is still not clear. The neuro-oncologists should pay attention to the systematic survey for extraneural metastasis of the GB. Timely detection and early treatment improve overall quality of patients’ life. Scientific Scholar 2023-06-23 /pmc/articles/PMC10316183/ /pubmed/37404487 http://dx.doi.org/10.25259/SNI_191_2023 Text en Copyright: © 2023 Surgical Neurology International https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-Share Alike 4.0 License, which allows others to remix, transform, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Case Report Achi, Jimmy Achi, Xavier Wong Veintimilla, Paula Cueva, Janina Unusual extraneural metastasis of glioblastoma |
title | Unusual extraneural metastasis of glioblastoma |
title_full | Unusual extraneural metastasis of glioblastoma |
title_fullStr | Unusual extraneural metastasis of glioblastoma |
title_full_unstemmed | Unusual extraneural metastasis of glioblastoma |
title_short | Unusual extraneural metastasis of glioblastoma |
title_sort | unusual extraneural metastasis of glioblastoma |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10316183/ https://www.ncbi.nlm.nih.gov/pubmed/37404487 http://dx.doi.org/10.25259/SNI_191_2023 |
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