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β1 integrin is essential for blood–brain barrier integrity under stable and vascular remodelling conditions; effects differ with age

BACKGROUND: Maintaining a tight blood–brain barrier (BBB) is an important prerequisite for the preservation of neurological health, though current evidence suggests it declines with age. While extracellular matrix-integrin interactions play critical roles in regulating the balance between vascular s...

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Detalles Bibliográficos
Autores principales: Halder, Sebok K., Delorme-Walker, Violaine D., Milner, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10316581/
https://www.ncbi.nlm.nih.gov/pubmed/37400852
http://dx.doi.org/10.1186/s12987-023-00453-0