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HDAC3 promotes macrophage pyroptosis via regulating histone deacetylation in acute lung injury

Activated inflammation and pyroptosis in macrophage are closely associated with acute lung injury (ALI). Histone deacetylase 3 (HDAC3) serves as an important enzyme that could repress gene expression by mediating chromatin remodeling. In this study, we found that HDAC3 was highly expressed in lung t...

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Detalles Bibliográficos
Autores principales: Li, Ning, Liu, Bohao, He, Ruyuan, Li, Guorui, Xiong, Rui, Fu, Tinglv, Li, Donghang, Xu, Chenzhen, Wang, Bo, Geng, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10316655/
https://www.ncbi.nlm.nih.gov/pubmed/37404376
http://dx.doi.org/10.1016/j.isci.2023.107158