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HDAC3 promotes macrophage pyroptosis via regulating histone deacetylation in acute lung injury
Activated inflammation and pyroptosis in macrophage are closely associated with acute lung injury (ALI). Histone deacetylase 3 (HDAC3) serves as an important enzyme that could repress gene expression by mediating chromatin remodeling. In this study, we found that HDAC3 was highly expressed in lung t...
Autores principales: | Li, Ning, Liu, Bohao, He, Ruyuan, Li, Guorui, Xiong, Rui, Fu, Tinglv, Li, Donghang, Xu, Chenzhen, Wang, Bo, Geng, Qing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10316655/ https://www.ncbi.nlm.nih.gov/pubmed/37404376 http://dx.doi.org/10.1016/j.isci.2023.107158 |
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