Epigenetic plasticity cooperates with cell-cell interactions to direct pancreatic tumorigenesis

INTRODUCTION: Virtually all cancers begin with genetic alteration in healthy cells, yet mounting evidence suggests that non-genetic events such as environmental signaling play a crucial role in unleashing tumorigenesis. In the pancreas, epithelial cells harboring an activating mutation in the Kras p...

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Detalles Bibliográficos
Autores principales: Burdziak, Cassandra, Alonso-Curbelo, Direna, Walle, Thomas, Reyes, José, Barriga, Francisco M., Haviv, Doron, Xie, Yubin, Zhao, Zhen, Zhao, Chujun Julia, Chen, Hsuan-An, Chaudhary, Ojasvi, Masilionis, Ignas, Choo, Zi-Ning, Gao, Vianne, Luan, Wei, Wuest, Alexandra, Ho, Yu-Jui, Wei, Yuhong, Quail, Daniela F, Koche, Richard, Mazutis, Linas, Chaligné, Ronan, Nawy, Tal, Lowe, Scott W., Pe’er, Dana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10316746/
https://www.ncbi.nlm.nih.gov/pubmed/37167403
http://dx.doi.org/10.1126/science.add5327

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