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Clinical Features and Management of Women with Borderline Ovarian Tumors in a Single Center in Brazil

Objective The aim of the present study was to describe and analyze data of 57 women with borderline ovarian tumors (BOTs) regarding histological characteristics, clinical features and treatment management at the Department of Obstetrics and Gynecology of the Universidade Estadual de Campinas (Unicam...

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Autores principales: Yoshida, Adriana, Tavares, Bárbara Virginia Gonçalves, Sarian, Luís Otavio, Andrade, Liliana Aparecida Lucci Ângelo, Derchain, Sophie Françoise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Revinter Publicações Ltda 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10316797/
https://www.ncbi.nlm.nih.gov/pubmed/30991432
http://dx.doi.org/10.1055/s-0039-1683415
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author Yoshida, Adriana
Tavares, Bárbara Virginia Gonçalves
Sarian, Luís Otavio
Andrade, Liliana Aparecida Lucci Ângelo
Derchain, Sophie Françoise
author_facet Yoshida, Adriana
Tavares, Bárbara Virginia Gonçalves
Sarian, Luís Otavio
Andrade, Liliana Aparecida Lucci Ângelo
Derchain, Sophie Françoise
author_sort Yoshida, Adriana
collection PubMed
description Objective The aim of the present study was to describe and analyze data of 57 women with borderline ovarian tumors (BOTs) regarding histological characteristics, clinical features and treatment management at the Department of Obstetrics and Gynecology of the Universidade Estadual de Campinas (Unicamp, in the Portuguese acronym). Methods The present retrospective study analyzed data obtained from clinical and histopathological reports of women with BOTs treated in a single cancer center between 2010 and 2018. Results A total of 57 women were included, with a mean age of 48.42 years old (15.43–80.77), of which 30 (52.63%) were postmenopausal, and 18 (31.58%) were < 40 years old. All of the women underwent surgery. A total of 37 women (64.91%) were submitted to complete surgical staging for BOT, and none (0/57) were submitted to pelvic or paraortic lymphadenectomy. Chemotherapy was administered for two patients who recurred. The final histological diagnoses were: serous in 20 (35.09%) cases, mucinous in 26 (45.61%), seromucinous in 10 (17.54%), and endometrioid in 1 (1.75%) case. Intraoperative analyses of frozen sections were obtained in 42 (73.68%) women, of which 28 (66.67%) matched with the final diagnosis. The mean follow-up was of 42.79 months (range: 2.03–104.87 months). Regarding the current status of the women, 45 (78.95%) are alive without disease, 2 (3.51%) are alive with disease, 9 (15.79%) had their last follow-up visit > 1 year before the performance of the present study but are alive, and 1 patient (1.75%) died of another cause. Conclusion Women in the present study were treated according to the current guidelines and only two patients recurred.
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spelling pubmed-103167972023-07-27 Clinical Features and Management of Women with Borderline Ovarian Tumors in a Single Center in Brazil Yoshida, Adriana Tavares, Bárbara Virginia Gonçalves Sarian, Luís Otavio Andrade, Liliana Aparecida Lucci Ângelo Derchain, Sophie Françoise Rev Bras Ginecol Obstet Objective The aim of the present study was to describe and analyze data of 57 women with borderline ovarian tumors (BOTs) regarding histological characteristics, clinical features and treatment management at the Department of Obstetrics and Gynecology of the Universidade Estadual de Campinas (Unicamp, in the Portuguese acronym). Methods The present retrospective study analyzed data obtained from clinical and histopathological reports of women with BOTs treated in a single cancer center between 2010 and 2018. Results A total of 57 women were included, with a mean age of 48.42 years old (15.43–80.77), of which 30 (52.63%) were postmenopausal, and 18 (31.58%) were < 40 years old. All of the women underwent surgery. A total of 37 women (64.91%) were submitted to complete surgical staging for BOT, and none (0/57) were submitted to pelvic or paraortic lymphadenectomy. Chemotherapy was administered for two patients who recurred. The final histological diagnoses were: serous in 20 (35.09%) cases, mucinous in 26 (45.61%), seromucinous in 10 (17.54%), and endometrioid in 1 (1.75%) case. Intraoperative analyses of frozen sections were obtained in 42 (73.68%) women, of which 28 (66.67%) matched with the final diagnosis. The mean follow-up was of 42.79 months (range: 2.03–104.87 months). Regarding the current status of the women, 45 (78.95%) are alive without disease, 2 (3.51%) are alive with disease, 9 (15.79%) had their last follow-up visit > 1 year before the performance of the present study but are alive, and 1 patient (1.75%) died of another cause. Conclusion Women in the present study were treated according to the current guidelines and only two patients recurred. Thieme Revinter Publicações Ltda 2019-03 /pmc/articles/PMC10316797/ /pubmed/30991432 http://dx.doi.org/10.1055/s-0039-1683415 Text en https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Yoshida, Adriana
Tavares, Bárbara Virginia Gonçalves
Sarian, Luís Otavio
Andrade, Liliana Aparecida Lucci Ângelo
Derchain, Sophie Françoise
Clinical Features and Management of Women with Borderline Ovarian Tumors in a Single Center in Brazil
title Clinical Features and Management of Women with Borderline Ovarian Tumors in a Single Center in Brazil
title_full Clinical Features and Management of Women with Borderline Ovarian Tumors in a Single Center in Brazil
title_fullStr Clinical Features and Management of Women with Borderline Ovarian Tumors in a Single Center in Brazil
title_full_unstemmed Clinical Features and Management of Women with Borderline Ovarian Tumors in a Single Center in Brazil
title_short Clinical Features and Management of Women with Borderline Ovarian Tumors in a Single Center in Brazil
title_sort clinical features and management of women with borderline ovarian tumors in a single center in brazil
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10316797/
https://www.ncbi.nlm.nih.gov/pubmed/30991432
http://dx.doi.org/10.1055/s-0039-1683415
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