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Targeted, programmable, and precise tandem duplication in the mammalian genome

Tandem duplications are frequent structural variations of the genome and play important roles in genetic disease and cancer. However, interpreting the phenotypic consequences of tandem duplications remains challenging, in part owing to the lack of genetic tools to model such variations. Here, we dev...

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Detalles Bibliográficos
Autores principales: Jiao, Yaoge, Li, Min, He, Xingyu, Wang, Yanhong, Song, Junwei, Hu, Yun, Li, Li, Zhou, Lifang, Jiang, Lurong, Qu, Junyan, Xie, Lifang, Chen, Qiang, Yao, Shaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10317127/
https://www.ncbi.nlm.nih.gov/pubmed/37295844
http://dx.doi.org/10.1101/gr.277261.122