Myosin in chromosome organisation and gene expression

The importance of myosin motor protein is well-characterised within the cytoplasm and cytoskeleton. However, mounting evidence on four nuclear myosins highlights the central role these proteins have in maintaining genomic stability and gene expression. This review focuses on each of their critical r...

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Detalles Bibliográficos
Autores principales: Shahid-Fuente, Isabel W., Toseland, Christopher P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2023
Materias:
Review Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10317160/
https://www.ncbi.nlm.nih.gov/pubmed/37171068
http://dx.doi.org/10.1042/BST20220939
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author Shahid-Fuente, Isabel W.
Toseland, Christopher P.
author_facet Shahid-Fuente, Isabel W.
Toseland, Christopher P.
author_sort Shahid-Fuente, Isabel W.
collection PubMed
description The importance of myosin motor protein is well-characterised within the cytoplasm and cytoskeleton. However, mounting evidence on four nuclear myosins highlights the central role these proteins have in maintaining genomic stability and gene expression. This review focuses on each of their critical roles in chromatin structure, chromosome translocation, transcription regulation, and DNA damage repair in terms of maintaining chromosome and chromatin integrity.
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spelling pubmed-103171602023-07-04 Myosin in chromosome organisation and gene expression Shahid-Fuente, Isabel W. Toseland, Christopher P. Biochem Soc Trans Review Articles The importance of myosin motor protein is well-characterised within the cytoplasm and cytoskeleton. However, mounting evidence on four nuclear myosins highlights the central role these proteins have in maintaining genomic stability and gene expression. This review focuses on each of their critical roles in chromatin structure, chromosome translocation, transcription regulation, and DNA damage repair in terms of maintaining chromosome and chromatin integrity. Portland Press Ltd. 2023-06-28 2023-05-12 /pmc/articles/PMC10317160/ /pubmed/37171068 http://dx.doi.org/10.1042/BST20220939 Text en © 2023 The Author(s) https://creativecommons.org/licenses/by/4.0/This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) (https://creativecommons.org/licenses/by/4.0/) . Open access for this article was enabled by the participation of University of Sheffield in an all-inclusive Read & Publish agreement with Portland Press and the Biochemical Society under a transformative agreement with JISC.
spellingShingle Review Articles
Shahid-Fuente, Isabel W.
Toseland, Christopher P.
Myosin in chromosome organisation and gene expression
title Myosin in chromosome organisation and gene expression
title_full Myosin in chromosome organisation and gene expression
title_fullStr Myosin in chromosome organisation and gene expression
title_full_unstemmed Myosin in chromosome organisation and gene expression
title_short Myosin in chromosome organisation and gene expression
title_sort myosin in chromosome organisation and gene expression
topic Review Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10317160/
https://www.ncbi.nlm.nih.gov/pubmed/37171068
http://dx.doi.org/10.1042/BST20220939
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