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The assembly of the MCM2–7 hetero-hexamer and its significance in DNA replication

The mini-chromosome maintenance proteins 2–7 (MCM2–7) hexamer is a protein complex that is key for eukaryotic DNA replication, which occurs only once per cell cycle. To achieve DNA replication, eukaryotic cells developed multiple mechanisms that control the timing of the loading of the hexamer onto...

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Detalles Bibliográficos
Autores principales: Hatoyama, Yuki, Kanemaki, Masato T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10317167/
https://www.ncbi.nlm.nih.gov/pubmed/37145026
http://dx.doi.org/10.1042/BST20221465

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