Alpha-1-antitrypsin antagonizes COVID-19: a review of the epidemiology, molecular mechanisms, and clinical evidence

Alpha-1-antitrypsin (AAT), a serine protease inhibitor (serpin), is increasingly recognized to inhibit SARS-CoV-2 infection and counter many of the pathogenic mechanisms of COVID-19. Herein, we reviewed the epidemiologic evidence, the molecular mechanisms, and the clinical evidence that support this...

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Detalles Bibliográficos
Autores principales: Bai, Xiyuan, Schountz, Tony, Buckle, Ashley M., Talbert, Janet L., Sandhaus, Robert A., Chan, Edward D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2023
Materias:
Review Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10317171/
https://www.ncbi.nlm.nih.gov/pubmed/37294003
http://dx.doi.org/10.1042/BST20230078

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10317171/
https://www.ncbi.nlm.nih.gov/pubmed/37294003
http://dx.doi.org/10.1042/BST20230078

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