Cargando…

Data-driven neuropathological staging and subtyping of TDP-43 proteinopathies

Mostrar otras versiones (1)

TAR DNA-binding protein-43 (TDP-43) accumulation is the primary pathology underlying several neurodegenerative diseases. Charting the progression and heterogeneity of TDP-43 accumulation is necessary to better characterize TDP-43 proteinopathies, but current TDP-43 staging systems are heuristic and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Young, Alexandra L, Vogel, Jacob W, Robinson, John L, McMillan, Corey T, Ossenkoppele, Rik, Wolk, David A, Irwin, David J, Elman, Lauren, Grossman, Murray, Lee, Virginia M Y, Lee, Edward B, Hansson, Oskar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10317181/ https://www.ncbi.nlm.nih.gov/pubmed/37150879 http://dx.doi.org/10.1093/brain/awad145

Ejemplares similares

Data-driven neuropathological staging and subtyping of TDP-43 proteinopathies
por: Young, Alexandra L, et al.
Publicado: (2023)

Molecular Neuropathology of TDP-43 Proteinopathies
por: Neumann, Manuela
Publicado: (2009)

Mechanisms and models of TDP-43 proteinopathies
por: Petrucelli, Leonard
Publicado: (2012)

Drosophila Answers to TDP-43 Proteinopathies
por: Romano, Maurizio, et al.
Publicado: (2012)

The basis of clinicopathological heterogeneity in TDP-43 proteinopathy
por: Kawakami, Ito, et al.
Publicado: (2019)

Mechanisms of TDP-43 Proteinopathy Onset and Propagation
por: Chen, Han-Jou, et al.
Publicado: (2021)

Propagation of TDP-43 proteinopathy in neurodegenerative disorders
por: Keszycki, Rachel, et al.
Publicado: (2021)

TDP-43 Proteinopathy Specific Biomarker Development
por: Cordts, Isabell, et al.
Publicado: (2023)

Rodent Models of TDP-43 Proteinopathy: Investigating the Mechanisms of TDP-43-Mediated Neurodegeneration
por: Gendron, Tania F., et al.
Publicado: (2011)

Genome wide analysis reveals heparan sulfate epimerase modulates TDP-43 proteinopathy
por: Liachko, Nicole F., et al.
Publicado: (2019)

Functional implication of ubiquitinating and deubiquitinating mechanisms in TDP-43 proteinopathies
por: Tran, Non-Nuoc, et al.
Publicado: (2022)

TDP-43 mislocalization drives neurofilament changes in a novel model of TDP-43 proteinopathy
por: Atkinson, Rachel, et al.
Publicado: (2021)

Mitochondrion-Dependent Cell Death in TDP-43 Proteinopathies
por: Lucini, Chantal B., et al.
Publicado: (2021)

Understanding In Vitro Pathways to Drug Discovery for TDP-43 Proteinopathies
por: Cheng, Hei W. A., et al.
Publicado: (2022)

Association of TDP-43 proteinopathy, cerebral amyloid angiopathy, and Lewy bodies with cognitive impairment in individuals with or without Alzheimer’s disease neuropathology
por: Thomas, David X., et al.
Publicado: (2020)

Single Versus Repetitive Traumatic Brain Injury: Current Knowledge on the Chronic Outcomes, Neuropathology and the Role of TDP-43 Proteinopathy
por: Janković, Tamara, et al.
Publicado: (2023)

Neurotoxic microglia promote TDP-43 proteinopathy in progranulin deficiency
por: Zhang, Jiasheng, et al.
Publicado: (2020)

Divergent Histopathological Networks of Frontotemporal Degeneration Proteinopathy Subytpes
por: Chen, Min, et al.
Publicado: (2022)

TDP-43 proteinopathy in Theiler’s murine encephalomyelitis virus infection
por: Masaki, Katsuhisa, et al.
Publicado: (2019)

TDP-43 proteinopathies: a new wave of neurodegenerative diseases
por: de Boer, Eva Maria Johanna, et al.
Publicado: (2021)

TDP-43 Proteinopathy and Tauopathy: Do They Have Pathomechanistic Links?
por: Riku, Yuichi, et al.
Publicado: (2022)

TDP-43 Proteinopathy and ALS: Insights into Disease Mechanisms and Therapeutic Targets
por: Scotter, Emma L., et al.
Publicado: (2015)

RNA-binding deficient TDP-43 drives cognitive decline in a mouse model of TDP-43 proteinopathy
por: Necarsulmer, Julie C, et al.
Publicado: (2023)

Neuronal overexpression of hTDP-43 in Caenorhabditis elegans mimics the cellular pathology commonly observed in TDP-43 proteinopathies
por: Koopman, Mandy, et al.
Publicado: (2023)

Disease Animal Models of TDP-43 Proteinopathy and Their Pre-Clinical Applications
por: Liu, Yu-Chih, et al.
Publicado: (2013)

Reviewing the Potential Links between Viral Infections and TDP-43 Proteinopathies
por: Rahic, Zerina, et al.
Publicado: (2023)

Neuropathological potential of FUS and TDP-43 in flies
Publicado: (2011)

Long non-coding RNA NEAT1_1 ameliorates TDP-43 toxicity in in vivo models of TDP-43 proteinopathy
por: Matsukawa, Koji, et al.
Publicado: (2021)

Nuclear import receptors are recruited by FG-nucleoporins to rescue hallmarks of TDP-43 proteinopathy
por: Khalil, Bilal, et al.
Publicado: (2022)

Facial Onset Sensory and Motor Neuronopathy: Further Evidence for a TDP-43 Proteinopathy
por: Ziso, Besa, et al.
Publicado: (2015)

Distinct responses of neurons and astrocytes to TDP-43 proteinopathy in amyotrophic lateral sclerosis
por: Smethurst, Phillip, et al.
Publicado: (2020)

Expanding the TDP-43 Proteinopathy Pathway From Neurons to Muscle: Physiological and Pathophysiological Functions
por: Versluys, Lauren, et al.
Publicado: (2022)

Diffuse argyrophilic grain disease with TDP-43 proteinopathy and neuronal intermediate filament inclusion disease: FTLD with mixed tau, TDP-43 and FUS pathologies
por: Koga, Shunsuke, et al.
Publicado: (2023)

Clinical Significance of TDP-43 Neuropathology in Amyotrophic Lateral Sclerosis
por: Cykowski, Matthew D., et al.
Publicado: (2017)

Widespread RNA metabolism impairment in sporadic inclusion body myositis TDP43-proteinopathy()
por: Cortese, Andrea, et al.
Publicado: (2014)

RRM adjacent TARDBP mutations disrupt RNA binding and enhance TDP-43 proteinopathy
por: Chen, Han-Jou, et al.
Publicado: (2019)

Restoring expression of Stathmin-2: a novel strategy to treat TDP-43 proteinopathies
por: Menge, Sonja, et al.
Publicado: (2023)

Microglial lysosome dysfunction contributes to white matter pathology and TDP-43 proteinopathy in GRN-associated FTD
por: Wu, Yanwei, et al.
Publicado: (2021)

TDP-43 proteinopathy impairs mRNP granule mediated postsynaptic translation and mRNA metabolism
por: Wong, Chia-En, et al.
Publicado: (2021)

HDAC1 dysregulation induces aberrant cell cycle and DNA damage in progress of TDP‐43 proteinopathies
por: Wu, Cheng‐Chun, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_1ok9j5nm02tu2kp4icfj83a63f