Data-driven neuropathological staging and subtyping of TDP-43 proteinopathies

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TAR DNA-binding protein-43 (TDP-43) accumulation is the primary pathology underlying several neurodegenerative diseases. Charting the progression and heterogeneity of TDP-43 accumulation is necessary to better characterize TDP-43 proteinopathies, but current TDP-43 staging systems are heuristic and...

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Detalles Bibliográficos
Autores principales: Young, Alexandra L, Vogel, Jacob W, Robinson, John L, McMillan, Corey T, Ossenkoppele, Rik, Wolk, David A, Irwin, David J, Elman, Lauren, Grossman, Murray, Lee, Virginia M Y, Lee, Edward B, Hansson, Oskar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10317181/
https://www.ncbi.nlm.nih.gov/pubmed/37150879
http://dx.doi.org/10.1093/brain/awad145
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