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Pyrazinamide-resistant Tuberculosis Obscured From Common Targeted Molecular Diagnostics

Here, we describe a clinical case of pyrazinamide-resistant (PZA-R) tuberculosis (TB) reported as PZA-susceptible (PZA-S) by common molecular diagnostics. Phenotypic susceptibility testing (pDST) indicated PZA-R TB. Targeted Sanger sequencing reported wild-type PncA, indicating PZA-S TB. Whole Genom...

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Detalles Bibliográficos
Autores principales:	Modlin, Samuel J., Mansjö, Mikael, Werngren, Jim, Ejike, Chidera M., Hoffner, Sven E., Valafar, Faramarz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10317212/ https://www.ncbi.nlm.nih.gov/pubmed/37043916 http://dx.doi.org/10.1016/j.drup.2023.100959

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