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18β-Glycyrrhetinic Acid Alleviates P. multocida-Induced Vascular Endothelial Inflammation by PARP1-Mediated NF-κB and HMGB1 Signalling Suppression in PIEC Cells

BACKGROUND: At present, the treatment and prevention of Pasteurella multocida infections in pigs mainly rely on antibiotics and vaccines, but inflammatory injury cannot be eliminated. The compound 18β-glycyrrhetinic acid (GA), a pentacyclic triterpenoid extracted from Glycyrrhiza glabra L. root (liq...

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Detalles Bibliográficos
Autores principales:	Lu, Qirong, Han, Wantong, Wen, Defeng, Guo, Pu, Liu, Yu, Wu, Zhongyuan, Fu, Shulin, Ye, Chun, Wang, Xu, Qiu, Yinsheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2023
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10317536/ https://www.ncbi.nlm.nih.gov/pubmed/37404255 http://dx.doi.org/10.2147/IDR.S413242

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