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Exercise hormone irisin is a critical regulator of cognitive function

Identifying secreted mediators driving the cognitive benefits of exercise holds great promise for the treatment of cognitive decline in aging or Alzheimer’s disease (AD). Here, we show that irisin, the cleaved and circulating form of the exercise-induced membrane protein FNDC5, is sufficient to conf...

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Detalles Bibliográficos
Autores principales: Islam, Mohammad R., Valaris, Sophia, Young, Michael F., Haley, Erin B., Luo, Renhao, Bond, Sabrina F., Mazuera, Sofia, Kitchen, Robert R., Caldarone, Barbara J., Bettio, Luis E.B., Christie, Brian R., Schmider, Angela B., Soberman, Roy J., Besnard, Antoine, Jedrychowski, Mark P., Kim, Hyeonwoo, Tu, Hua, Kim, Eunhee, Choi, Se Hoon, Tanzi, Rudolph E., Spiegelman, Bruce M., Wrann, Christiane D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10317538/
https://www.ncbi.nlm.nih.gov/pubmed/34417591
http://dx.doi.org/10.1038/s42255-021-00438-z