A case of eosinophilic bronchiolitis after the initiation of immune checkpoint inhibitor

A 50‐year‐old Japanese woman with advanced breast cancer presented with productive cough and dyspnea while she was receiving a sixth cycle of chemotherapy including atezolizumab. Chest computed tomography revealed bronchiolitis and transbronchial lung cryobiopsy revealed eosinophilic bronchiolitis....

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Autores principales: Tamura, Akiko, Hashimoto, Masao, Hosoi, Atsuko, Hojo, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2023
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10317597/
https://www.ncbi.nlm.nih.gov/pubmed/37201911
http://dx.doi.org/10.1111/1759-7714.14931
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author Tamura, Akiko
Hashimoto, Masao
Hosoi, Atsuko
Hojo, Masayuki
author_facet Tamura, Akiko
Hashimoto, Masao
Hosoi, Atsuko
Hojo, Masayuki
author_sort Tamura, Akiko
collection PubMed
description A 50‐year‐old Japanese woman with advanced breast cancer presented with productive cough and dyspnea while she was receiving a sixth cycle of chemotherapy including atezolizumab. Chest computed tomography revealed bronchiolitis and transbronchial lung cryobiopsy revealed eosinophilic bronchiolitis. Corticosteroid therapy successfully resolved her symptoms. Eosinophilic bronchiolitis is a rare but important immune‐related adverse event; herein, we discuss its diagnosis and possible pathophysiology.
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spelling pubmed-103175972023-07-04 A case of eosinophilic bronchiolitis after the initiation of immune checkpoint inhibitor Tamura, Akiko Hashimoto, Masao Hosoi, Atsuko Hojo, Masayuki Thorac Cancer Case Reports A 50‐year‐old Japanese woman with advanced breast cancer presented with productive cough and dyspnea while she was receiving a sixth cycle of chemotherapy including atezolizumab. Chest computed tomography revealed bronchiolitis and transbronchial lung cryobiopsy revealed eosinophilic bronchiolitis. Corticosteroid therapy successfully resolved her symptoms. Eosinophilic bronchiolitis is a rare but important immune‐related adverse event; herein, we discuss its diagnosis and possible pathophysiology. John Wiley & Sons Australia, Ltd 2023-05-18 /pmc/articles/PMC10317597/ /pubmed/37201911 http://dx.doi.org/10.1111/1759-7714.14931 Text en © 2023 The Authors. Thoracic Cancer published by China Lung Oncology Group and John Wiley & Sons Australia, Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
Tamura, Akiko
Hashimoto, Masao
Hosoi, Atsuko
Hojo, Masayuki
A case of eosinophilic bronchiolitis after the initiation of immune checkpoint inhibitor
title A case of eosinophilic bronchiolitis after the initiation of immune checkpoint inhibitor
title_full A case of eosinophilic bronchiolitis after the initiation of immune checkpoint inhibitor
title_fullStr A case of eosinophilic bronchiolitis after the initiation of immune checkpoint inhibitor
title_full_unstemmed A case of eosinophilic bronchiolitis after the initiation of immune checkpoint inhibitor
title_short A case of eosinophilic bronchiolitis after the initiation of immune checkpoint inhibitor
title_sort case of eosinophilic bronchiolitis after the initiation of immune checkpoint inhibitor
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10317597/
https://www.ncbi.nlm.nih.gov/pubmed/37201911
http://dx.doi.org/10.1111/1759-7714.14931
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