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RELA governs a network of islet-specific metabolic genes necessary for beta cell function

AIMS/HYPOTHESIS: NF-κB activation unites metabolic and inflammatory responses in many diseases yet less is known about the role that NF-κB plays in normal metabolism. In this study we investigated how RELA impacts the beta cell transcriptional landscape and provides network control over glucoregulat...

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Detalles Bibliográficos
Autores principales: Zammit, Nathan W., Wong, Ying Ying, Walters, Stacey N., Warren, Joanna, Barry, Simon C., Grey, Shane T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10317895/
https://www.ncbi.nlm.nih.gov/pubmed/37311878
http://dx.doi.org/10.1007/s00125-023-05931-6

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