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Disruption of cortical cell type composition and function underlies diabetes-associated cognitive decline

AIMS/HYPOTHESIS: Type 2 diabetes is associated with increased risk of cognitive decline although the pathogenic basis for this remains obscure. Deciphering diabetes-linked molecular mechanisms in cells of the cerebral cortex could uncover novel therapeutic targets. METHODS: Single-cell transcriptomi...

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Detalles Bibliográficos
Autores principales:	Little, Karis, Singh, Aditi, Del Marco, Angel, Llorián-Salvador, María, Vargas-Soria, Maria, Turch-Anguera, Mireia, Solé, Montse, Bakker, Noëlle, Scullion, Sarah, Comella, Joan X., Klaassen, Ingeborg, Simó, Rafael, Garcia-Alloza, Monica, Tiwari, Vijay K., Stitt, Alan W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10317904/ https://www.ncbi.nlm.nih.gov/pubmed/37351595 http://dx.doi.org/10.1007/s00125-023-05935-2

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