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Autophagy dictates sensitivity to PRMT5 inhibitor in breast cancer
Protein arginine methyltransferase 5 (PRMT5) catalyzes mono-methylation and symmetric di-methylation on arginine residues and has emerged as a potential antitumor target with inhibitors being tested in clinical trials. However, it remains unknown how the efficacy of PRMT5 inhibitors is regulated. He...
Autores principales: | Brobbey, Charles, Yin, Shasha, Liu, Liu, Ball, Lauren E., Howe, Philip H., Delaney, Joe R., Gan, Wenjian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318021/ https://www.ncbi.nlm.nih.gov/pubmed/37400460 http://dx.doi.org/10.1038/s41598-023-37706-9 |
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