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TRIM22 promotes the proliferation of glioblastoma cells by activating MAPK signaling and accelerating the degradation of Raf-1

The tripartite motif (TRIM) 22 and mitogen-activated protein kinase (MAPK) signaling pathways play critical roles in the growth of glioblastoma (GBM). However, the molecular mechanism underlying the relationship between TRIM22 and MAPK signaling remains unclear. Here, we found that TRIM22 binds to e...

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Detalles Bibliográficos
Autores principales: Fei, Xiaowei, Dou, Ya-nan, Sun, Kai, Wei, Jialiang, Guo, Qingdong, Wang, Li, Wu, Xiuquan, Lv, Weihao, Jiang, Xiaofan, Fei, Zhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318069/
https://www.ncbi.nlm.nih.gov/pubmed/37258577
http://dx.doi.org/10.1038/s12276-023-01007-y