piRNA-1742 promotes renal cell carcinoma malignancy by regulating USP8 stability through binding to hnRNPU and thereby inhibiting MUC12 ubiquitination

Accumulating studies have confirmed that PIWI-interacting RNAs (piRNAs) are considered epigenetic effectors in cancer. We performed piRNA microarray expression analysis on renal cell carcinoma (RCC) tumor tissues and paired normal tissues and performed a series of in vivo and in vitro experiments to...

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Detalles Bibliográficos
Autores principales: Zhang, Wentao, Zheng, Zongtai, Wang, Keyi, Mao, Weipu, Li, Xue, Wang, Guangchun, Zhang, Yuanyuan, Huang, Jianhua, Zhang, Ning, Wu, Pengfei, Liu, Ji, Zhang, Haimin, Che, Jianping, Peng, Bo, Zheng, Junhua, Li, Wei, Yao, Xudong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318070/
https://www.ncbi.nlm.nih.gov/pubmed/37332045
http://dx.doi.org/10.1038/s12276-023-01010-3

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