Human and murine fibroblast single-cell transcriptomics reveals fibroblast clusters are differentially affected by ageing and serum cholesterol

AIMS: Specific fibroblast markers and in-depth heterogeneity analysis are currently lacking, hindering functional studies in cardiovascular diseases (CVDs). Here, we established cell-type markers and heterogeneity in murine and human arteries and studied the adventitial fibroblast response to CVD an...

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Detalles Bibliográficos
Autores principales: van Kuijk, Kim, McCracken, Ian R, Tillie, Renée J H A, Asselberghs, Sebastiaan E J, Kheder, Dlzar A, Muitjens, Stan, Jin, Han, Taylor, Richard S, Wichers Schreur, Ruud, Kuppe, Christoph, Dobie, Ross, Ramachandran, Prakesh, Gijbels, Marion J, Temmerman, Lieve, Kirkwoord, Phoebe M, Luyten, Joris, Li, Yanming, Noels, Heidi, Goossens, Pieter, Wilson-Kanamori, John R, Schurgers, Leon J, Shen, Ying H, Mees, Barend M E, Biessen, Erik A L, Henderson, Neil C, Kramann, Rafael, Baker, Andrew H, Sluimer, Judith C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318398/
https://www.ncbi.nlm.nih.gov/pubmed/36718802
http://dx.doi.org/10.1093/cvr/cvad016

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