Cargando…

Combined GIP receptor and GLP1 receptor agonism attenuates NAFLD in male APOE∗3-Leiden.CETP mice

BACKGROUND: Combined glucose-dependent insulinotropic polypeptide receptor (GIPR) and glucagon-like peptide-1 receptor (GLP1R) agonism is superior to single GLP1R agonism with respect to glycemic control and weight loss in obese patients with or without type 2 diabetes. As insulin resistance and obe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ying, Zhixiong, van Eenige, Robin, Ge, Xiaoke, van Marwijk, Christy, Lambooij, Joost M., Guigas, Bruno, Giera, Martin, de Boer, Jan Freark, Coskun, Tamer, Qu, Hongchang, Wang, Yanan, Boon, Mariëtte R., Rensen, Patrick C.N., Kooijman, Sander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318458/ https://www.ncbi.nlm.nih.gov/pubmed/37379656 http://dx.doi.org/10.1016/j.ebiom.2023.104684

Ejemplares similares

Cannabinoid type 1 receptor inverse agonism attenuates dyslipidemia and atherosclerosis in APOE∗3-Leiden.CETP mice
por: van Eenige, Robin, et al.
Publicado: (2021)

Mild Exercise Does Not Prevent Atherosclerosis in APOE*3‐Leiden.CETP Mice or Improve Lipoprotein Profile of Men with Obesity
por: In het Panhuis, Wietse, et al.
Publicado: (2020)

Continuous Light Does Not Affect Atherosclerosis in APOE*3-Leiden.CETP Mice
por: Schilperoort, Maaike, et al.
Publicado: (2020)

Time-restricted feeding attenuates hypercholesterolaemia and atherosclerosis development during circadian disturbance in APOE∗3-Leiden.CETP mice
por: In Het Panhuis, Wietse, et al.
Publicado: (2023)

The prebiotic inulin modulates gut microbiota but does not ameliorate atherosclerosis in hypercholesterolemic APOE*3-Leiden.CETP mice
por: Hoving, Lisa R., et al.
Publicado: (2018)

Dose Effects of Ammonium Perfluorooctanoate on Lipoprotein Metabolism in APOE*3-Leiden.CETP Mice
por: Pouwer, Marianne G, et al.
Publicado: (2019)

Atherothrombosis model by silencing of protein C in APOE*3-Leiden.CETP transgenic mice
por: Jongejan, Yvonne K., et al.
Publicado: (2021)

Both Transient and Continuous Corticosterone Excess Inhibit Atherosclerotic Plaque Formation in APOE*3-Leiden.CETP Mice
por: Auvinen, Hanna E., et al.
Publicado: (2013)

Disruption of circadian rhythm by alternating light‐dark cycles aggravates atherosclerosis development in APOE*3‐Leiden.CETP mice
por: Schilperoort, Maaike, et al.
Publicado: (2019)

Niacin Reduces Atherosclerosis Development in APOE*3Leiden.CETP Mice Mainly by Reducing NonHDL-Cholesterol
por: Kühnast, Susan, et al.
Publicado: (2013)

A Systems Analysis of Phenotype Heterogeneity in APOE*3Leiden.CETP Mice Induced by Long-Term High-Fat High-Cholesterol Diet Feeding
por: Paalvast, Yared, et al.
Publicado: (2022)

Plasma and Liver Lipidomics Response to an Intervention of Rimonabant in ApoE*3Leiden.CETP Transgenic Mice
por: Hu, Chunxiu, et al.
Publicado: (2011)

Anti-PCSK9 antibodies inhibit pro-atherogenic mechanisms in APOE*3Leiden.CETP mice
por: Schuster, Susanne, et al.
Publicado: (2019)

A hierarchical dynamic model used for investigating feed efficiency and its relationship with hepatic gene expression in APOE*3‐Leiden.CETP mice
por: Zhang, Xiang, et al.
Publicado: (2021)

Akkermansia muciniphila Exerts Lipid‐Lowering and Immunomodulatory Effects without Affecting Neointima Formation in Hyperlipidemic APOE*3‐Leiden.CETP Mice
por: Katiraei, Saeed, et al.
Publicado: (2019)

Oncostatin M reduces atherosclerosis development in APOE*3Leiden.CETP mice and is associated with increased survival probability in humans
por: van Keulen, Danielle, et al.
Publicado: (2019)

Inflammatory cytokine oncostatin M induces endothelial activation in macro- and microvascular endothelial cells and in APOE*3Leiden.CETP mice
por: van Keulen, Danielle, et al.
Publicado: (2018)

Lipidomics Reveals Multiple Pathway Effects of a Multi-Components Preparation on Lipid Biochemistry in ApoE*3Leiden.CETP Mice
por: Wei, Heng, et al.
Publicado: (2012)

GIP receptor agonism blocks chemotherapy-induced nausea and vomiting
por: Borner, Tito, et al.
Publicado: (2023)

Male apoE*3‐Leiden.CETP mice on high‐fat high‐cholesterol diet exhibit a biphasic dyslipidemic response, mimicking the changes in plasma lipids observed through life in men
por: Paalvast, Yared, et al.
Publicado: (2017)

The AT04A vaccine against proprotein convertase subtilisin/kexin type 9 reduces total cholesterol, vascular inflammation, and atherosclerosis in APOE*3Leiden.CETP mice
por: Landlinger, Christine, et al.
Publicado: (2017)

Anorectic and aversive effects of GLP-1 receptor agonism are mediated by brainstem cholecystokinin neurons, and modulated by GIP receptor activation
por: Costa, Alessia, et al.
Publicado: (2021)

The Effects of Dual GLP-1/GIP Receptor Agonism on Glucagon Secretion—A Review
por: Mathiesen, David S., et al.
Publicado: (2019)

GIP Receptor Agonism Attenuates GLP-1 Receptor Agonist–Induced Nausea and Emesis in Preclinical Models
por: Borner, Tito, et al.
Publicado: (2021)

Male apoE*3‐Leiden.CETP mice on high‐fat high‐cholesterol diet exhibit a biphasic dyslipidemic response, mimicking the changes in plasma lipids observed through life in men
Publicado: (2018)

GIP receptor agonism improves dyslipidemia and atherosclerosis independently of body weight loss in preclinical mouse model for cardio-metabolic disease
por: Sachs, Stephan, et al.
Publicado: (2023)

“Let's Stay Together”; GIP and GLP-1 dual agonism in the treatment of metabolic disease
por: DiMarchi, Richard D.
Publicado: (2018)

Early but Not Late Exercise Training in Mice Exacerbates Hepatic Inflammation in Developing Nonalcoholic Fatty Liver Disease
por: Kovynev, Artemiy, et al.
Publicado: (2023)

Molecular mechanism of agonism and inverse agonism in ghrelin receptor
por: Qin, Jiao, et al.
Publicado: (2022)

Optimized GIP analogs promote body weight lowering in mice through GIPR agonism not antagonism
por: Mroz, Piotr A., et al.
Publicado: (2018)

Species‐specific action of (Pro3)GIP – a full agonist at human GIP receptors, but a partial agonist and competitive antagonist at rat and mouse GIP receptors
por: Sparre‐Ulrich, A H, et al.
Publicado: (2015)

Agonism and Antagonism at the Insulin Receptor
por: Knudsen, Louise, et al.
Publicado: (2012)

Chronic peptide-based GIP receptor inhibition exhibits modest glucose metabolic changes in mice when administered either alone or combined with GLP-1 agonism
por: West, Jason A., et al.
Publicado: (2021)

The Role of GIP Receptor in the CNS for the Pathogenesis of Obesity
por: Fukuda, Makoto
Publicado: (2021)

Marked Cortisol Production by Intracrine ACTH in GIP-Treated Cultured Adrenal Cells in Which the GIP Receptor Was Exogenously Introduced
por: Fujii, Hiroko, et al.
Publicado: (2014)

Kinetic basis of partial agonism at NMDA receptors
por: Kussius, Cassandra L, et al.
Publicado: (2009)

A simplified procedure to trace triglyceride‐rich lipoprotein metabolism in vivo
por: Ying, Zhixiong, et al.
Publicado: (2021)

Physiological roles of the GIP receptor in murine brown adipose tissue
por: Beaudry, Jacqueline L., et al.
Publicado: (2019)

Glucose-dependent insulinotropic polypeptide (GIP) and GIP receptor (GIPR) genes: An association analysis of polymorphisms and bone in young and elderly women
por: Garg, Gaurav, et al.
Publicado: (2015)

Enhanced agonist residence time, internalization rate and signalling of the GIP receptor variant [E354Q] facilitate receptor desensitization and long‐term impairment of the GIP system
por: Gabe, Maria Buur Nordskov, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_aas182snfeve2jlhv7p8oact2s