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Glutamine supplementation reverses manganese neurotoxicity by eliciting the mitochondrial unfolded protein response

Excessive exposure to manganese (Mn) can cause neurological abnormalities, but the mechanism of Mn neurotoxicity remains unclear. Previous studies have shown that abnormal mitochondrial metabolism is a crucial mechanism underlying Mn neurotoxicity. Therefore, improving neurometabolic in neuronal mit...

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Detalles Bibliográficos
Autores principales:	Zhang, Shixuan, Zhang, Junrou, Wu, Luli, Chen, Li, Niu, Piye, Li, Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318524/ https://www.ncbi.nlm.nih.gov/pubmed/37408687 http://dx.doi.org/10.1016/j.isci.2023.107136

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