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VBP1 negatively regulates CHIP and selectively inhibits the activity of hypoxia-inducible factor (HIF)-1α but not HIF-2α

Hypoxia-inducible factor-1 (HIF-1) is a critical transcription factor that regulates the expression of genes involved in cellular adaptation to low oxygen levels. Aberrant regulation of the HIF-1 signaling pathway is linked to various human diseases. Previous studies have established that HIF-1α is...

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Detalles Bibliográficos
Autores principales:	Yue, Yiming, Tang, Yanfei, Huang, Hao, Zheng, Dongdong, Liu, Cong, Zhang, Haifeng, Liu, Yunzhang, Li, Yun, Sun, Xiangrong, Lu, Ling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318525/ https://www.ncbi.nlm.nih.gov/pubmed/37201586 http://dx.doi.org/10.1016/j.jbc.2023.104829

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