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Measuring and maintaining organ perfusion in a patient with Takayasu's arteritis undergoing cardiac surgery*

Takayasu's arteritis is a rare vasculitis affecting the aorta and its branches. Disease progression can result in arterial stenosis and subsequent organ dysfunction. Estimating organ perfusion by measuring the peripheral blood pressure can be challenging because it may be altered by arterial st...

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Autores principales: Dan, K., Takahashi, K., Lefor, A. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318576/
https://www.ncbi.nlm.nih.gov/pubmed/37408768
http://dx.doi.org/10.1002/anr3.12236
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author Dan, K.
Takahashi, K.
Lefor, A. K.
author_facet Dan, K.
Takahashi, K.
Lefor, A. K.
author_sort Dan, K.
collection PubMed
description Takayasu's arteritis is a rare vasculitis affecting the aorta and its branches. Disease progression can result in arterial stenosis and subsequent organ dysfunction. Estimating organ perfusion by measuring the peripheral blood pressure can be challenging because it may be altered by arterial stenosis. We report the case of a 61‐year‐old woman with Takayasu's arteritis with aortic and mitral regurgitation who presented for aortic valve replacement and mitral valvuloplasty. Peripheral arterial pressure was considered a less reliable surrogate for organ perfusion because the patient had diminished blood flow in both the lower and upper extremities. In addition to the bilateral radial arterial pressure, the blood pressure in the ascending aorta was monitored to estimate the patient's organ perfusion pressure during cardiopulmonary bypass. The initial target blood pressure was determined based on the pre‐operative baseline and modified by measurement of the aortic pressure. Cerebral oximetry using near‐infrared spectroscopy and mixed venous saturation was monitored to estimate oxygen supply‐demand balance, which helped evaluate cerebral perfusion and determine the transfusion threshold. The entire procedure was uneventful, and no organ dysfunction was observed postoperatively.
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spelling pubmed-103185762023-08-04 Measuring and maintaining organ perfusion in a patient with Takayasu's arteritis undergoing cardiac surgery* Dan, K. Takahashi, K. Lefor, A. K. Anaesth Rep Case Report Takayasu's arteritis is a rare vasculitis affecting the aorta and its branches. Disease progression can result in arterial stenosis and subsequent organ dysfunction. Estimating organ perfusion by measuring the peripheral blood pressure can be challenging because it may be altered by arterial stenosis. We report the case of a 61‐year‐old woman with Takayasu's arteritis with aortic and mitral regurgitation who presented for aortic valve replacement and mitral valvuloplasty. Peripheral arterial pressure was considered a less reliable surrogate for organ perfusion because the patient had diminished blood flow in both the lower and upper extremities. In addition to the bilateral radial arterial pressure, the blood pressure in the ascending aorta was monitored to estimate the patient's organ perfusion pressure during cardiopulmonary bypass. The initial target blood pressure was determined based on the pre‐operative baseline and modified by measurement of the aortic pressure. Cerebral oximetry using near‐infrared spectroscopy and mixed venous saturation was monitored to estimate oxygen supply‐demand balance, which helped evaluate cerebral perfusion and determine the transfusion threshold. The entire procedure was uneventful, and no organ dysfunction was observed postoperatively. John Wiley and Sons Inc. 2023-07-04 /pmc/articles/PMC10318576/ /pubmed/37408768 http://dx.doi.org/10.1002/anr3.12236 Text en © 2023 The Authors. Anaesthesia Reports published by John Wiley & Sons Ltd on behalf of Association of Anaesthetists. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Dan, K.
Takahashi, K.
Lefor, A. K.
Measuring and maintaining organ perfusion in a patient with Takayasu's arteritis undergoing cardiac surgery*
title Measuring and maintaining organ perfusion in a patient with Takayasu's arteritis undergoing cardiac surgery*
title_full Measuring and maintaining organ perfusion in a patient with Takayasu's arteritis undergoing cardiac surgery*
title_fullStr Measuring and maintaining organ perfusion in a patient with Takayasu's arteritis undergoing cardiac surgery*
title_full_unstemmed Measuring and maintaining organ perfusion in a patient with Takayasu's arteritis undergoing cardiac surgery*
title_short Measuring and maintaining organ perfusion in a patient with Takayasu's arteritis undergoing cardiac surgery*
title_sort measuring and maintaining organ perfusion in a patient with takayasu's arteritis undergoing cardiac surgery*
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318576/
https://www.ncbi.nlm.nih.gov/pubmed/37408768
http://dx.doi.org/10.1002/anr3.12236
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