Tanshinone I specifically suppresses NLRP3 inflammasome activation by disrupting the association of NLRP3 and ASC

BACKGROUND: Abnormal activation of NLRP3 inflammasome is related to a series of inflammatory diseases, including type 2 diabetes, gouty arthritis, non-alcoholic steatohepatitis (NASH), and neurodegenerative disorders. Therefore, targeting NLRP3 inflammasome is regarded as a potential therapeutic str...

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Detalles Bibliográficos
Autores principales: Zhao, Jia, Liu, Hongbin, Hong, Zhixian, Luo, Wei, Mu, Wenqing, Hou, Xiaorong, Xu, Guang, Fang, Zhie, Ren, Lutong, Liu, Tingting, Wen, Jincai, Shi, Wei, Wei, Ziying, Yang, Yongping, Zou, Wenjun, Zhao, Jun, Xiao, Xiaohe, Bai, Zhaofang, Zhan, Xiaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318668/
https://www.ncbi.nlm.nih.gov/pubmed/37400760
http://dx.doi.org/10.1186/s10020-023-00671-0

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