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Serine protease PRSS56, a novel cancer-testis antigen activated by DNA hypomethylation, promotes colorectal and gastric cancer progression via PI3K/AKT axis

BACKGROUND: Cancer/testis (CT) antigens/genes are usually overexpressed in cancers and exhibit high immunogenicity, making them promising targets for immunotherapy and cancer vaccines. The role of serine protease PRSS56 in cancers remains unknown to date. METHODS: RNA sequencing studies were perform...

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Detalles Bibliográficos
Autores principales:	Li, Dandan, Xia, Lingyun, Huang, Pan, Wang, Zidi, Guo, Qiwei, Huang, Congcong, Leng, Weidong, Qin, Shanshan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318715/ https://www.ncbi.nlm.nih.gov/pubmed/37400936 http://dx.doi.org/10.1186/s13578-023-01060-0

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