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Overexpression of human alpha-Synuclein leads to dysregulated microbiome/metabolites with ageing in a rat model of Parkinson disease

BACKGROUND: Braak’s hypothesis states that sporadic Parkinson’s disease (PD) follows a specific progression of pathology from the peripheral to the central nervous system, and this progression can be monitored by detecting the accumulation of alpha-Synuclein (α-Syn) protein. Consequently, there is g...

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Detalles Bibliográficos
Autores principales:	Singh, Yogesh, Trautwein, Christoph, Romani, Joan, Salker, Madhuri S., Neckel, Peter H., Fraccaroli, Isabel, Abeditashi, Mahkameh, Woerner, Nils, Admard, Jakob, Dhariwal, Achal, Dueholm, Morten K. D., Schäfer, Karl-Herbert, Lang, Florian, Otzen, Daniel E., Lashuel, Hilal A., Riess, Olaf, Casadei, Nicolas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318726/ https://www.ncbi.nlm.nih.gov/pubmed/37403161 http://dx.doi.org/10.1186/s13024-023-00628-1

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