Systematic discovery of gene fusions in pediatric cancer by integrating RNA-seq and WGS

BACKGROUND: Gene fusions are important cancer drivers in pediatric cancer and their accurate detection is essential for diagnosis and treatment. Clinical decision-making requires high confidence and precision of detection. Recent developments show RNA sequencing (RNA-seq) is promising for genome-wid...

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Detalles Bibliográficos
Autores principales: van Belzen, Ianthe A. E. M., Cai, Casey, van Tuil, Marc, Badloe, Shashi, Strengman, Eric, Janse, Alex, Verwiel, Eugène T. P., van der Leest, Douwe F. M., Kester, Lennart, Molenaar, Jan J., Meijerink, Jules, Drost, Jarno, Peng, Weng Chuan, Kerstens, Hindrik H. D., Tops, Bastiaan B. J., Holstege, Frank C. P., Kemmeren, Patrick, Hehir-Kwa, Jayne Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318758/
https://www.ncbi.nlm.nih.gov/pubmed/37400763
http://dx.doi.org/10.1186/s12885-023-11054-3

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