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The time-course of cancer cachexia onset reveals biphasic transcriptional disruptions in female skeletal muscle distinct from males

BACKGROUND: Cancer-cachexia (CC) is a debilitating condition affecting up to 80% of cancer patients and contributing to 40% of cancer-related deaths. While evidence suggests biological sex differences in the development of CC, assessments of the female transcriptome in CC are lacking, and direct com...

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Detalles Bibliográficos
Autores principales: Morena da Silva, Francielly, Lim, Seongkyun, Cabrera, Ana Regina, Schrems, Eleanor R., Jones, Ronald G., Rosa-Caldwell, Megan E., Washington, Tyrone A., Murach, Kevin A., Greene, Nicholas P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318789/
https://www.ncbi.nlm.nih.gov/pubmed/37403010
http://dx.doi.org/10.1186/s12864-023-09462-7